Jolie revealed during a chat on Anderson that she and Pitt are funding a clinic in Ethiopia in honor of their daughter Zahara Marley, who was born in the country.
The Hollywood superstars have also built a children’s medical center in Cambodia for their son Maddox.
Pitt and Jolie plan to create several more charities in order to teach their children the value of philanthropy and keep them in touch with their home countries.
“They have programs in their countries [for] each of them we’re starting. There’s a TB/AIDS clinic being built for Zahara; there’s a clinic already for Mad,” Jolie told Anderson Cooper.
The actress continued: “So each of them will take that responsibility. They are from their country and they are of their country and they should know that, it’s part of their family, we are their family but so is their country.”
Jolie recently acknowledged that she was living a “self-destructive” lifestyle until she began her own charity work as a UN Goodwill Ambassador.
Her directorial debut In The Land of Blood and Honey, which has netted her a Golden Globe nomination, opens in US cinemas on December 23. A UK release date has yet to be announced.
Jolie’s full interview on Anderson airs on Monday (December 19).